| 11:00 PM | Local Programming |
| 11:35 PM | Nightline: In-depth reporting on news and events with Cynthia McFadden, Terry Moran and Martin Bashir. |
| 12:06 AM | Jimmy Kimmel Live: Kate Walsh; ``Dancing With the Stars''; Paramore. |
| 1:06 AM | Oprah Winfrey: Dr. Oz investigates medical mysteries including primordial dwarfism and photographic memories. |
| 2:05 AM | Cribs: Songwriter Dallas Austin; boxer Floyd Mayweather; singer Lumidee. |
| 2:35 AM | Local Programming |
| 3:05 AM | ABC World News Now: Global news. |
| 4:30 AM | America This Morning: Breaking news. |
| 5:00 AM | Local Programming |
| 7:00 AM | Good Morning America: Il Divo performs; musician Quincy Jones. |
| 9:00 AM | Live With Regis and Kelly - Holiday SOS Week: David Cook performs; fashionably frugal party ideas. |
| 10:00 AM | Rachael Ray: The ultimate Thanksgiving feast; a butcher's turkey tips. |
| 11:00 AM | The View: Denis Leary; transsexual man who gave birth; David Foster; Katharine McPhee. |
| 12:00 PM | Local Programming |
| 12:30 PM | Who Wants to Be a Millionaire |
| 1:00 PM | All My Children: Colby suggests that Brot should hide out at the mansion. |
| 2:00 PM | One Life to Live: Marty and Todd come face to face; Blair tells Starr the truth about what Todd did. |
| 3:00 PM | General Hospital: Tracy finds that the rug has been pulled out from under her. |
| 4:00 PM | Oprah Winfrey: Actors Brad Pitt and Cate Blanchett (``The Curious Case of Benjamin Button''). |
| 5:00 PM | Local Programming |
| 6:30 PM | ABC's World News With Charles Gibson: The latest world and national news. |
| 7:00 PM | Jeopardy! |
| 7:30 PM | Wheel of Fortune - Wheel Goes Waikoloa |
| 8:00 PM | Pushing Daisies - Oh Oh Oh ... It's Magic: Ned agrees to help a famed magician whose animal assistants are being killed off. |
| 9:00 PM | Private Practice - Serving Two Masters: Addison treats two pregnant women who unwittingly share the same husband. |
| 10:01 PM | Dirty Sexy Money - The Injured Party: Tripp invites an injured bicyclist to recuperate at the Darling mansion. |
| 11:00 PM | Local Programming |
| 11:35 PM | Nightline: In-depth reporting on news and events with Cynthia McFadden, Terry Moran and Martin Bashir. |